AIDS cure Journal Nature published research report monkey version HIV take refuge from anti-AIDS drugs. The findings come just days after the disappointing announcement.
The monkey version of HIV can take refuge from anti-AIDS drugs.
Within days of entering the body, a study said Sunday, dampening hopes for a human cure.
If the same holds true for human beings, treatment may have to start “extremely early” after a person is infected with the virus that causes AIDS, according to researchers publishing in the journal Nature.
The findings come just days after the disappointing announcement that a Mississippi baby thought to cleared of HIV.
Through a potent dose of antivirals administered 30 hours.
After birth and continued for 18 months, has tested positive for the virus after two drug-free years.
The unfortunate clinical findings of viral rebound in the Mississippi baby appear to concordant with the monkey data.
Study co-author Dan Barouch of the Beth Israel Deaconess Medical Centre (BIDMC) in Massachusetts told
AIDS cure Journal Nature published research report monkey version HIV take refuge from anti-AIDS drugs.
The authors of the Nature paper stressed their findings yet to confirmed in humans.
These data certainly raise important challenges for HIV eradication efforts.”
A key challenge for curing HIV infection the presence of viral reservoirs — infected immune cells.
AIDS cure Journal Nature published research report monkey version HIV take refuge from anti-AIDS drugs.
In which virus DNA can lie dormant for years, undisturbed by antiretroviral treatment (ART) or the immune system.
In the vast majority of people, the virus starts proliferating as soon as treatment stopped, which means the drugs to take for life.
Little known about when and where these reservoir cells established during HIV infection.
Some assumed the reservoirs “seeded” by virus DNA during acute HIV infection — when the presence of virus in the blood had already risen to a high level.
But the new study found that in rhesus monkeys infected with simian HIV, or SIV, the reservoir established “strikingly early” after infection.
